From the A3 take the exit "Rottendorf" and follow the B8 to Würzburg. At the traffic light in Würzburg take the left-hand lane onto Stadtring Süd in the direction of Ansbach / Schwäbisch Hall. Leave the Stadtring Süd at the the Frauenland / Stadtmitte exit and head for the Stadtmitte (city centre). Follow the signs to the Residenz car park ("Parkplatz Residenz").
From the A7 take the exit "Estenfeld" and follow the B19 to Würzburg (ca. 7 km). Get in the left-hand lane before the Würzburg place name sign and continue straight on (Stadtring Süd) in the direction of Ansbach / Schwäbisch Hall. Leave the Stadtring Süd at the Frauenland / Stadtmitte exit and head for the Stadtmitte (city centre). Follow the signs to the Residenz car park ("Parkplatz Residenz").
Please see the travel service of Deutsche Bahn on how to get to Würzburg central station.
From there take the tram (lines 1,3,5) to "Dom". Walk past the Würzburger Dom and follow the Hofstraße to the Residenz.
Frankfurt Airport: Take the ICE train from Frankfurt Airport long distance train station to Würzburg central station (Hbf) (1.5h)
Nürnberg Airport: Take the U2 to Nürnberg central station (Hbf). From there take the ICE train to Würzburg central station (Hbf) (1.5h)
Munich Airport: Take the Metro (S1 or S8) to Munich central central station (Hbf). From there take the ICE train to Würzburg central station (Hbf) (3h)